Chapter 79. Chapter 79. Metastatic Solid Tumors to Bone

  1. ASBMR
  1. Gregory R. Mundy and
  2. Julie A. Sterling

Published Online: 23 DEC 2009

DOI: 10.1002/9780470623992.ch79

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

How to Cite

ASBMR (2008) Chapter 79. Metastatic Solid Tumors to Bone, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470623992.ch79

Publication History

  1. Published Online: 23 DEC 2009
  2. Published Print: 18 NOV 2008

ISBN Information

Print ISBN: 9780977888214

Online ISBN: 9780470623992

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Keywords:

  • osteolytic tumors;
  • osteoblastic tumors;
  • and metastasis to bone

Summary

This chapter contains sections titled:

  • Importance of the Problem

  • Spectrum of Bone Metastases

  • Concept of the Vicious Cycle

  • Cellular Mechanisms of Osteolytic Bone Metastasis

  • Osteoblast Impairment in Osteolytic Metastases

  • Osteoblastic Metastases

  • Concept of the Premetastatic Niche

  • Preclinical Models of Bone Metastases

  • Clinical Manifestations of Bone Metastases

  • Osteoporosis

  • Management