Chapter 12. Pseudomonas Exotoxin A-Based Immunotoxins for Targeted Cancer Therapy

  1. Arsénio M. Fialho2 and
  2. Ananda M. Chakrabarty3
  1. Philipp Wolf and
  2. Ursula Elsässer-Beile

Published Online: 18 AUG 2010

DOI: 10.1002/9780470626528.ch12

Emerging Cancer Therapy

Emerging Cancer Therapy

How to Cite

Wolf, P. and Elsässer-Beile, U. (2010) Pseudomonas Exotoxin A-Based Immunotoxins for Targeted Cancer Therapy, in Emerging Cancer Therapy (eds A. M. Fialho and A. M. Chakrabarty), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470626528.ch12

Editor Information

  1. 2

    Institute for Biotechnology and Bioengineering (IBB), Center for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisbon, Portugal

  2. 3

    Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, USA

Author Information

  1. Department of Urology, Experimental Urology, University Hospital Freiburg, Freiburg, Germany

Publication History

  1. Published Online: 18 AUG 2010
  2. Published Print: 16 JUL 2010

ISBN Information

Print ISBN: 9780470444672

Online ISBN: 9780470626528



  • pseudomonas exotoxin A-based immunotoxins - in targeted cancer therapy;
  • pseudomonas exotoxin A-based immunotoxins;
  • protein engineering - increasing efficacy of PE–based immunotoxins


This chapter contains sections titled:

  • Introduction

  • Pseudomonas Aeruginosa

  • Pseudomonas Exotoxin A

  • Pseudomonas Exotoxin A-Based Immunotoxins

  • Conclusions

  • References