(Degenerate Ring Transformation of Heterocycles)
Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. ANRORC Rearrangement. Comprehensive Organic Name Reactions and Reagents. 20:87–90.
- Published Online: 15 SEP 2010
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ANRORC rearrangement is a very common transformation for heterocycles, and has been discovered for more than a century already. It occurs in nucleophilic substitution of heterocyclic compounds, and stands for a whole process of the initial addition of a nucleophile, followed by the ring opening and ring closure during the substitution. This transformation is also known as SN(ANRORC) reaction or degenerate ring transformation. This reaction has been reported to consist two subgroups with either an “outside” leaving group or “inside” leaving group. This rearrangement reaction has wide applications in heterocycle chemistry.
- nucleophilic substitution;
- heterocyclic ring;