Baeyer Diarylmethane Synthesis
Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. Baeyer Diarylmethane Synthesis. Comprehensive Organic Name Reactions and Reagents. 31:132–135.
- Published Online: 15 SEP 2010
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Acid-catalyzed condensation of aromatic compounds with formaldehyde or formaldehyde derivatives is generally known as Baeyer diarylmethane synthesis. Reactive benzene derivatives such as phenols and arylamines have been applied to condense with formaldehyde and only a small number of less-reactive aromatics have been used in this reaction. A reasonable yield about 70–80% has been obtained from this type of the reaction. This reaction has been reviewed extensively to synthesize diarylmethanes. Many other reactions also have been developed to synthesize diarylmethanes The study finds that the condensation occurs at the para-position of substituted aromatics.