Baeyer Oxindole Synthesis
Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. Baeyer Oxindole Synthesis. Comprehensive Organic Name Reactions and Reagents. 34:144–146.
- Published Online: 15 SEP 2010
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Oxindole is synthesized via the acidic reduction of o-nitrophenylacetic acid by tin and the subsequent cyclization of the resulting reduced intermediate. This reaction is known as Baeyer oxindole synthesis. Several other acidic reducing combinations can also be applied to preparation of oxindole.
- o-nitrophenylacetic acid;
- palladium catalyst;