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Balz-Schiemann Reaction

Published Online: 15 SEP 2010

DOI: 10.1002/9780470638859.conrr044

Comprehensive Organic Name Reactions and Reagents

Comprehensive Organic Name Reactions and Reagents

How to Cite

2010. Balz-Schiemann Reaction. Comprehensive Organic Name Reactions and Reagents. 44:185–190.

Publication History

  1. Published Online: 15 SEP 2010

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Abstract

In this reaction, a fluorine atom is introduced into aromatic rings through the thermal decomposition of diazonium tetrafluoroborate by diazotization of the corresponding aromatic amines. This reaction is generally known as the Balz–Schiemann reaction. This reaction is especially important for synthesizing the specifically fluorinated aromatic compounds, of which the decomposition in the absence of solvent normally affords a fairly good yield of aromatic fluorides. The Balz–Schiemann reaction has been extensively reviewed and has been found useful in the preparation of aromatic halides.

Keywords:

  • diazotization;
  • aromatic halides;
  • dichloromethane;
  • fluorinated aromatic compounds