Cadogan-Sundberg Indole Synthesis
Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. Cadogan-Sundberg Indole Synthesis. Comprehensive Organic Name Reactions and Reagents. 128:585–588.
- Published Online: 15 SEP 2010
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The formation of indole from the reduction of o-nitrostyrenes is referred to as the Cadogan–Sundberg indole synthesis. This reaction is based on initial work of Cadogan for the preparation of carbazole by the reductive cyclization of aromatic nitro compounds with triethyl phosphite. This reaction is useful for the preparation of indole derivatives.
- triethyl phosphite;