Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. Einhorn Acylation. Comprehensive Organic Name Reactions and Reagents. 209:967–970.
- Published Online: 15 SEP 2010
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The acylation of alcohols using anhydride or acyl halide in a tertiary amine such as pyridine is known as the Einhorn acylation. The tertiary amines have been identified as both nucleophilic acylation catalyst and acid scavenger. Numerous highly nucleophilic tertiary amines have been employed for this reaction. This reaction has been applied in the preparation of esters from alcohols and acylation reagents.
- tertiary amines;
- 4-(dimethylamino)pyridine (DMAP)