Published Online: 15 SEP 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Comprehensive Organic Name Reactions and Reagents
How to Cite
2010. Eisleb Alkylation. Comprehensive Organic Name Reactions and Reagents. 211:974–976.
- Published Online: 15 SEP 2010
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The alkylation of compounds of active hydrogen with alkyl halide via the treatment of sodium amide is generally known as Eisleb alkylation. Various compounds with active hydrogens have been reported suitable for this reaction. The introduction of N,N-dialkylamino alkyl group to compounds with an active proton has proven valuable in producing high yield.
- alkyl halide;
- sodium amide;
- N,N-dialkylamino alkyl group