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Hayashi Rearrangement

Published Online: 15 SEP 2010

DOI: 10.1002/9780470638859.conrr300

Comprehensive Organic Name Reactions and Reagents

Comprehensive Organic Name Reactions and Reagents

How to Cite

2010. Hayashi Rearrangement. Comprehensive Organic Name Reactions and Reagents. 300:1347–1349.

Publication History

  1. Published Online: 15 SEP 2010

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Abstract

The rearrangement substituted o-benzoylbenzoic acids in the presence of sulfuric acid or phosphorous pentoxide is referred to as Hayashi rearrangement. It has been found that the direction of carbonium center transfer is determined by sulfuric acid concentration and reaction temperature. Various catalysts have been tried, such as trifluoroacetic acid, methanesulfonic acid, and PPA and found no effect on this rearrangement. Naphthalenes and benzhydryls also show similar reactions. This rearrangement has been found only in limited cases.

Keywords:

  • Hayashi rearrangement;
  • o-benzoylbenzoic acid;
  • trifluoroacetic acid;
  • naphthalenes