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Reppe Carbonylation

Published Online: 15 SEP 2010

DOI: 10.1002/9780470638859.conrr530

Comprehensive Organic Name Reactions and Reagents

Comprehensive Organic Name Reactions and Reagents

How to Cite

2010. Reppe Carbonylation. Comprehensive Organic Name Reactions and Reagents. 530:2352–2357.

Publication History

  1. Published Online: 15 SEP 2010

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Abstract

This reaction is a three-component reaction to transform unsaturated hydrocarbons and carbon monoxide into a variety of saturated or unsaturated acids, esters, or anhydrides using a CO complex of group VIII transition metals as a catalyst with water, alcohol, or acid as a nucleophile, respectively and is generally known as the Reppe carbonylation. It has been reported that the cobalt and palladium complexes are the most active catalysts for this reaction. In addition, this reaction is tolerable for a wide variety of functional groups and is thermodynamically favored process. The reactivity order for the carbonylation of alkenes and alkynes and the effect of water on the rate of reaction for the carbonylation of alkynes have been discussed. It has been observed that the nature of the base plays an important role in controlling the reaction path. This reaction is useful for various applications in industrial manipulation.

Keywords:

  • carbon monoxide (CO);
  • group VIII transition metals;
  • iron-carbon monoxide complex;
  • hydrogen