Standard Article

Wagner-Jauregg Reaction

Published Online: 15 SEP 2010

DOI: 10.1002/9780470638859.conrr654

Comprehensive Organic Name Reactions and Reagents

Comprehensive Organic Name Reactions and Reagents

How to Cite

2010. Wagner-Jauregg Reaction. Comprehensive Organic Name Reactions and Reagents. 654:2926–2929.

Publication History

  1. Published Online: 15 SEP 2010

Chemistry Terms

Choose one or more boxes to highlight terms.

Abstract

The double Diels–Alder reaction between maleic anhydride and 1,1-diarylethylenes followed by rearomatization to form higher aromatic analogs is generally known as the Wagner–Jauregg reaction. Likewise, the corresponding products are known as the Wagner–Jauregg adducts. In contrast, the occurrence of this reaction strongly depends on the steric effect. This reaction has certain application in the preparation of polyaromatic compounds.

Keywords:

  • 1-phenyl-1-(o-methyl)phenyl ethylene;
  • hydrogen halide;
  • maleic anhydride;
  • 1,1-diphenyl ethylene