Chapter 8. Implications of Biofilm Formation in Chronic Wounds and in Cystic Fibrosis

  1. Tamilvanan Shunmugaperumal

Published Online: 29 JUN 2010

DOI: 10.1002/9780470640463.ch8

Biofilm Eradication and Prevention: A Pharmaceutical Approach to Medical Device Infections

Biofilm Eradication and Prevention: A Pharmaceutical Approach to Medical Device Infections

How to Cite

Shunmugaperumal, T. (2010) Implications of Biofilm Formation in Chronic Wounds and in Cystic Fibrosis, in Biofilm Eradication and Prevention: A Pharmaceutical Approach to Medical Device Infections, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470640463.ch8

Author Information

  1. Department of Pharmaceutical Technology, International Medical University, Kuala Lumpur, Malaysia

Publication History

  1. Published Online: 29 JUN 2010
  2. Published Print: 22 JUL 2010

ISBN Information

Print ISBN: 9780470479964

Online ISBN: 9780470640463

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Keywords:

  • biofilm formation implications - in chronic wounds and in cystic fibrosis (CF);
  • composite fiber structures and antibacterial drugs - for wound healing applications;
  • chronic P. aeruginosa lung infection in CF - mucoid phenotype, producing alginate in vitro and in patients

Summary

This chapter contains sections titled:

  • Introduction

  • Characteristics of Chronic Wounds

  • The Host Response

  • The Bacterial Host-Infection Versus Colonization

  • Recent Hypothesis in Chronic Wound

  • Future Work and Perspectives

  • Wound Dressings

  • Wound Dressings Based on Synthetic Polymers

  • Wound Dressings Based on Natural Polymers

  • Composite Fiber Structures Loaded with Antibacterial Drugs for Wound Healing Applications

  • Cystic Fibrosis

  • P. Aeruginosa Biofilms and the Immune Response in CF

  • Antibiotic Therapy of P. Aeruginosa Lung Infection

  • Aerosol Delivery to the Lung

  • Iron and Chelated Iron as Antibiofilm Drugs for CF

  • Quorum-Sensing Inhibitors as Antibiofilm Drug For CF

  • References