16. Developmental Neurotoxicity of Anticholinesterase Pesticides

  1. Tetsuo Satoh2,3,4 and
  2. Ramesh C. Gupta5
  1. John Flaskos and
  2. Magdalini Sachana

Published Online: 28 MAR 2011

DOI: 10.1002/9780470640500.ch16

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

How to Cite

Flaskos, J. and Sachana, M. (2011) Developmental Neurotoxicity of Anticholinesterase Pesticides, in Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology (eds T. Satoh and R. C. Gupta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470640500.ch16

Editor Information

  1. 2

    Department of Pharmacology and Toxicology, Japan

  2. 3

    Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

  3. 4

    HAB Research Institute, Ichikawa, Chiba, Japan

  4. 5

    Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA

Author Information

  1. Laboratory of Biochemistry and Toxicology, School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece

Publication History

  1. Published Online: 28 MAR 2011
  2. Published Print: 18 JAN 2011

ISBN Information

Print ISBN: 9780470410301

Online ISBN: 9780470640500

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Keywords:

  • developmental neurotoxicity of anticholinesterase pesticides;
  • developmental neurotoxicity - prenatal or postnatal exposure, developing organism to neurotoxic insult;
  • anticholinesterase pesticide effect - on neurite outgrowth

Summary

This chapter contains sections titled:

  • Introduction

  • The Basis for the Increased Vulnerability of the Developing Nervous System Compared to the Adult

  • Developmental Neurotoxicants and Anticholinesterase Pesticides

  • The Developmental Neurotoxicity of Anticholinesterase Pesticides as a Result of Pharmacokinetic Differences Between the Young and the Adult

  • The Developmental Neurotoxicity of Anticholinesterase Pesticides as a Result of Interference with Neurodevelopmental Processes

  • Effects of Anticholinesterase Pesticides on Neuronal Cell Replication and Differentiation

  • Effects of Anticholinesterase Pesticides on Neurite Outgrowth

  • Effects of Anticholinesterase Pesticides on Synaptic Development

  • Effects of Anticholinesterase Pesticides on Glial Development

  • Effects of Anticholinesterase Pesticides on Apoptosis

  • Effects of Anticholinesterase Pesticides on Neurobehavior

  • Testing for Developmental Neurotoxicity: The Use of Anticholinesterase Pesticides as Testing Agents

  • Conclusions

  • References