20. Novel Biomarkers of Organophosphate Exposure

  1. Tetsuo Satoh4,5,6 and
  2. Ramesh C. Gupta7
  1. Tetsuo Satoh4,5,6,
  2. Salmaan H. Inayat-Hussain1,
  3. Michihiro Kamijima2 and
  4. Jun Ueyama3

Published Online: 28 MAR 2011

DOI: 10.1002/9780470640500.ch20

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

How to Cite

Satoh, T., Inayat-Hussain, S. H., Kamijima, M. and Ueyama, J. (2011) Novel Biomarkers of Organophosphate Exposure, in Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology (eds T. Satoh and R. C. Gupta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470640500.ch20

Editor Information

  1. 4

    Department of Pharmacology and Toxicology, Japan

  2. 5

    Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

  3. 6

    HAB Research Institute, Ichikawa, Chiba, Japan

  4. 7

    Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA

Author Information

  1. 1

    Faculty of Allied Health Sciences, Universiti Kebangsaan Malaysia, Jaran RajaMuda Abdul Aziz, Kuala Lumpur, Malaysia

  2. 2

    Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

  3. 3

    Department of Medicinal Technology, Nagoya University School of Health Sciences, Higashi-ku, Nagoya, Japan

  4. 4

    Department of Pharmacology and Toxicology, Japan

  5. 5

    Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

  6. 6

    HAB Research Institute, Ichikawa, Chiba, Japan

Publication History

  1. Published Online: 28 MAR 2011
  2. Published Print: 18 JAN 2011

ISBN Information

Print ISBN: 9780470410301

Online ISBN: 9780470640500

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Keywords:

  • novel biomarkers of organophosphate exposure;
  • simple quantitative determination - of urinary metabolites of OPs;
  • biological monitoring data of urinary DAPs from adults and children - environmental OP contamination

Summary

This chapter contains sections titled:

  • Introduction

  • Plasma β-Glucuronidase as a Novel Biomarker for Organophosphate Exposure in Rats

  • Plasma β-Glucuronidase as a Novel Human Biomarker for Anticholinesterase Pesticide Exposure in the Malaysian Population

  • Development of a Simple Quantitative Determination of Urinary Metabolites of OPs and the Relationship between BG Activity and Urinary Metabolite Contents After Occupational OP Exposure in the Human Population

  • Conclusions

  • References