22. Anticholinesterase Pesticides Interactions

  1. Tetsuo Satoh2,3,4 and
  2. Ramesh C. Gupta5
  1. Ramesh C. Gupta5 and
  2. Dejan Milatovic1

Published Online: 28 MAR 2011

DOI: 10.1002/9780470640500.ch22

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

How to Cite

Gupta, R. C. and Milatovic, D. (2011) Anticholinesterase Pesticides Interactions, in Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology (eds T. Satoh and R. C. Gupta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470640500.ch22

Editor Information

  1. 2

    Department of Pharmacology and Toxicology, Japan

  2. 3

    Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan

  3. 4

    HAB Research Institute, Ichikawa, Chiba, Japan

  4. 5

    Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA

Author Information

  1. 1

    Vanderbilt University Medical Center, Department of Pediatrics/Pediatric Toxicology, Vanderbilt University, Nashville, Tennessee, USA

  2. 5

    Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA

Publication History

  1. Published Online: 28 MAR 2011
  2. Published Print: 18 JAN 2011

ISBN Information

Print ISBN: 9780470410301

Online ISBN: 9780470640500

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Keywords:

  • anticholinesterase pesticides interactions;
  • organophosphorus (OP) and N-methylcarbamate (CM) insecticides - controlling pests;
  • metabolism-based interactions - OP and CM insecticides, metabolized in tissues

Summary

This chapter contains sections titled:

  • Introduction

  • Interaction between Cholinesterase Inhibitors

  • Interaction between ChE Inhibitors and non-ChE Inhibitors

  • Are OPs Inhibitors or Substrates of Carboxylesterases?

  • Potentiation of Toxicity of OP Insecticides by Their Impurities

  • Metabolism-Based Interactions

  • Models for Interaction Investigation

  • Conclusions

  • References