Chapter 37. Phenomenology and Treatment of Bipolar I Disorder in Children: A Critical Review

  1. Lakshmi N. Yatham2 and
  2. Mario Maj3
  1. Gabrielle A. Carlson and
  2. Elizabeth B. Weller

Published Online: 13 AUG 2010

DOI: 10.1002/9780470661277.ch37

Bipolar Disorder

Bipolar Disorder

How to Cite

Carlson, G. A. and Weller, E. B. (2010) Phenomenology and Treatment of Bipolar I Disorder in Children: A Critical Review, in Bipolar Disorder (eds L. N. Yatham and M. Maj), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470661277.ch37

Editor Information

  1. 2

    Department of Psychiatry, The University of British Columbia, Vancouver, Canada

  2. 3

    Department of Psychiatry, University of Naples SUN, Naples, Italy

Author Information

  1. Department of Child and Adolescent Psychiatry, Stony Brook University School of Medicine, Putnam Hall-South Campus, Stony Brook, NY 11794-8790, USA

Publication History

  1. Published Online: 13 AUG 2010
  2. Published Print: 1 OCT 2010

ISBN Information

Print ISBN: 9780470721988

Online ISBN: 9780470661277



  • phenomenology and treatment of bipolar I disorder in children - a critical review;
  • under-diagnosis of bipolar I disorder - focus in adult as well as child and adolescent psychiatry;
  • affective oscillation, many times a day - called ultradian cycling;
  • bipolar disorder into classical ‘narrow phenotype’ - and ‘severe mood dysregulation’ (SMD);
  • Massachusetts General Hospital approach – mania, extremely severe ‘irritability’ or affective aggression;
  • true comorbidity, comorbid condition present - episode of mania or depression fully subsided;
  • Course and Outcome of Bipolar Youth study (COBY) - including children and adolescents;
  • substance abuse and schizophrenia - important differential diagnoses in teens;
  • mania and bipolar I disorder, 2007 American Academy of Child and Adolescent Psychiatry (AACAP) Practice Parameter and treatment recommendations;
  • child mania rating scale - for children


This chapter contains sections titled:

  • Introduction

  • The ‘bipolar controversy’

  • Clinical phenomenology

  • Comorbidities

  • Course

  • Offspring studies

  • Assessment

  • Treatment

  • Conclusion

  • References