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Atomic Force Microscopy (AFM)

Techniques

  1. Janne T. Hyotyla,
  2. Roderick Y. H. Lim

Published Online: 15 MAR 2012

DOI: 10.1002/9780470661345.smc043

Supramolecular Chemistry: From Molecules to Nanomaterials

Supramolecular Chemistry: From Molecules to Nanomaterials

How to Cite

Hyotyla, J. T. and Lim, R. Y. H. 2012. Atomic Force Microscopy (AFM). Supramolecular Chemistry: From Molecules to Nanomaterials. .

Author Information

  1. University of Basel, Basel, Switzerland

Publication History

  1. Published Online: 15 MAR 2012

Abstract

Atomic force microscopy (AFM) is a stylus-based technique that uses sub-nanonewton force sensitivity to image surfaces at sub-nanometer resolution. As a surface-sensitive tool, AFM is ideal for investigating the properties and local morphology of surface-grafted supramolecules and (bio)polymers, which play important roles in mediating interfacial processes ranging from tribology to colloidal stability and biology. Moreover, the versatility of AFM to operate in diverse environments (i.e., air, liquid, or vacuum) adds to its appeal in comparison to other surface methods. Given its capability for high-resolution imaging, force measurements, and nanomechanical manipulation, AFM is directly applicable to studies of stimuli-responsive polymers, biomaterials, and polymeric nanostructures.

Keywords:

  • atomic force microsope (AFM);
  • nanomechanics;
  • biomaterials;
  • stimuli-responsive polymers;
  • polymer brush;
  • nanostructure;
  • biointerfaces