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Azacoronands and Azacyclophanes

Molecular Recognition

  1. Antonio Bianchi1,
  2. Enrique García-España2

Published Online: 15 MAR 2012

DOI: 10.1002/9780470661345.smc048

Supramolecular Chemistry: From Molecules to Nanomaterials

Supramolecular Chemistry: From Molecules to Nanomaterials

How to Cite

Bianchi, A. and García-España, E. 2012. Azacoronands and Azacyclophanes. Supramolecular Chemistry: From Molecules to Nanomaterials. .

Author Information

  1. 1

    University of Florence, Florence, Italy

  2. 2

    Universidad de Valencia, Valencia, Spain

Publication History

  1. Published Online: 15 MAR 2012

Abstract

Azacycloalkanes and azacyclophanes are among the first macrocyclic ligands developed in the field of supramolecular chemistry. Since they are polyamines, they show dual nature in the coordination of both metal cations, when they are in the free-base form, and anionic species, when they are protonated. As a matter of fact, they played a key role in the birth of macrocyclic chemistry of transition metal complexes and anion coordination chemistry. Furthermore, azacyclophanes fostered also the birth of apolar complexation in aqueous solution, since their aromatic units act as binding sites for apolar substrates.

Keywords:

  • azacycloalkanes;
  • azacyclophanes;
  • metal complexes;
  • anion complexes;
  • apolar complexation;
  • binding of neutral molecules;
  • azamacrocycles;
  • polyamines