Cyclodextrins: From Nature to Nanotechnology
Published Online: 15 MAR 2012
Copyright © 2012 John Wiley & Sons, Ltd. All rights reserved.
Supramolecular Chemistry: From Molecules to Nanomaterials
How to Cite
Lincoln, S. F. and Pham, D.-T. 2012. Cyclodextrins: From Nature to Nanotechnology. Supramolecular Chemistry: From Molecules to Nanomaterials. .
- Published Online: 15 MAR 2012
Cyclodextrins (CDs) are naturally occurring homochiral macrocycles composed of α-1,4-linked d-glucopyranose in the 4C1 conformation. The three smallest α-, β-, and γ-CDs are composed of 6, 7, and 8 glucopyranoses, and as a class constitute one of the most widely used molecular components in supramolecular chemistry. This usage is based on the ability of CDs to complex a vast range of guests in their hydrophobic annuli in water. In this brief review, CD supramolecular chemistry is explored from simple CD complexes to increasingly complex assemblies. The modification of CDs to give desirable properties is also examined along with their supramolecular chemistry. This exploration encompasses CD host–guest complexes, enantioselectivity, polymers, catalysis, metallocyclodextrins, rotaxanes and catenanes, and molecular devices and nanomachines, some of which mimic Nature and all of which represent a fascinating aspect of supramolecular chemistry with some extraordinary possibilities for further advances and practical application.
- host–guest complex;
- molecular device;