Standard Article

Amide and Urea-Based Receptors

Molecular Recognition

  1. Md. Alamgir Hossain1,
  2. Rowshan A. Begum2,
  3. Victor W. Day2,
  4. Kristin Bowman-James2

Published Online: 15 MAR 2012

DOI: 10.1002/9780470661345.smc063

Supramolecular Chemistry: From Molecules to Nanomaterials

Supramolecular Chemistry: From Molecules to Nanomaterials

How to Cite

Hossain, M. A., Begum, R. A., Day, V. W. and Bowman-James, K. 2012. Amide and Urea-Based Receptors. Supramolecular Chemistry: From Molecules to Nanomaterials. .

Author Information

  1. 1

    Jackson State University, Jackson, MS, USA

  2. 2

    University of Kansas, Lawrence, KS, USA

Publication History

  1. Published Online: 15 MAR 2012

Abstract

The chemistry, binding, and structure of amide- and urea-based receptors, as well as its thioamide- and thiourea-based corollaries are described. The chapter begins with a short historical introduction of these hosts as ligands for anions, followed by a description of their chemical properties, including similarities and differences in bonding. The remainder of the chapter provides examples of the two types of receptors, the monodentate amides/thioamides, and the chelating ureas/thioureas, in order of increasing dimensionality, that is, acyclic, monocyclic, and bicyclic and higher order hosts. Features such as common (and different) structural motifs, preorganization, and the unique chemistry of some of these hosts and their guests are described.

Keywords:

  • anion coordination;
  • urea hosts;
  • thiourea hosts;
  • amide hosts;
  • thioamide hosts;
  • hydrogen bonding;
  • structure