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Self-Assembly of Nucleic Acids


  1. Karina M. M. Carneiro,
  2. Pik Kwan Lo,
  3. Hanadi F. Sleiman

Published Online: 15 MAR 2012

DOI: 10.1002/9780470661345.smc086

Supramolecular Chemistry: From Molecules to Nanomaterials

Supramolecular Chemistry: From Molecules to Nanomaterials

How to Cite

Carneiro, K. M. M., Lo, P. K. and Sleiman, H. F. 2012. Self-Assembly of Nucleic Acids. Supramolecular Chemistry: From Molecules to Nanomaterials. .

Author Information

  1. McGill University, Montreal, Quebec, Canada

Publication History

  1. Published Online: 15 MAR 2012


DNA has emerged as a powerful building block for the construction of supramolecular materials, because of its molecular recognition specificity, programmability through sequence selection, ease of functionalization, an array of enzyme-assisted modifications, and automated synthesis. This molecule has been used to create a variety of constructs, ranging from extended materials, such as two-dimensional (2D) lattices and networks and one-dimensional (1D) fibers and nanotubes, to controlled and discrete three-dimensional (3D) nanostructures, such as polygons and cages, and it has also been used to compose bulk materials such as hydrogels and crystals. This review focuses on the different approaches in DNA nanotechnology, the resulting 2D- and 3D-DNA nanostructures, and their emerging applications in biology and materials science.


  • DNA;
  • nanotechnology;
  • self-assembly;
  • programmable structures;
  • two-dimensional networks;
  • three-dimensional cages;
  • nanotubes;
  • nanoparticles;
  • transition metals