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Mechanical Preparation of Crystalline Materials. An Oxymoron?

Supramolecular Materials Chemistry

  1. Dario Braga1,
  2. Elena Dichiarante2,
  3. Fabrizia Grepioni1,
  4. Giulio I. Lampronti1,
  5. Lucia Maini1,
  6. Paolo P. Mazzeo1,
  7. Simone D'Agostino1

Published Online: 15 MAR 2012

DOI: 10.1002/9780470661345.smc115

Supramolecular Chemistry: From Molecules to Nanomaterials

Supramolecular Chemistry: From Molecules to Nanomaterials

How to Cite

Braga, D., Dichiarante, E., Grepioni, F., Lampronti, G. I., Maini, L., Mazzeo, P. P. and D'Agostino, S. 2012. Mechanical Preparation of Crystalline Materials. An Oxymoron?. Supramolecular Chemistry: From Molecules to Nanomaterials. .

Author Information

  1. 1

    University of Bologna, Bologna, Italy

  2. 2

    PolyCrystalLine s.r.l., Medicina, Bologna, Italy

Publication History

  1. Published Online: 15 MAR 2012

Abstract

The thesis developed in this chapter is that reactions taking place between molecular materials (intersolid) or within a molecular material (intrasolid) can be used to produce new crystalline materials in solvent-free conditions and often with quantitative yields. The most common approach to intersolid and, to lesser extent, intrasolid processes is based on the mechanical cogrinding of the solid reactants, which implies comminution of the reactants. The implicit consequence of this is the lack of crystals of the product suitable for single-crystal X-ray diffraction. The mechanical process yields a polycrystalline or amorphous product, with structure and composition that often differ from that obtained from solution crystallization.

Keywords:

  • solid-state reactions;
  • mechanochemistry;
  • polymorphism;
  • crystal forms;
  • cocrystals;
  • coordination networks