Replication Processes—From Autocatalysis to Systems Chemistry
Published Online: 15 MAR 2012
Copyright © 2012 John Wiley & Sons, Ltd. All rights reserved.
Supramolecular Chemistry: From Molecules to Nanomaterials
How to Cite
Huck, J. and Philp, D. 2012. Replication Processes—From Autocatalysis to Systems Chemistry. Supramolecular Chemistry: From Molecules to Nanomaterials. .
- Published Online: 15 MAR 2012
Chemical systems capable of templating and catalyzing their own synthesis — known as replicating systems — have started to appear in the chemical literature over the last 25 years. In a biological context, these systems represent a link with the origin of life, and their behavior could perhaps provide a model for prebiotic chemical evolution. For the synthetic chemist, they represent the ultimate synthetic machine, capable of directing the formation of a large number of identical copies of themselves from a single template molecule. One of the driving forces in this research area has been recognizing the important role that replication plays in biology and attempting to answer a fundamental question — “Is the structural complexity of nucleic acids necessary to store and transmit information at a molecular level”? In addition, the concept of a chemical template that is capable of making billions of exact copies of itself, given appropriate starting materials, is a highly attractive one for the emerging field of systems chemistry. The development of a detailed understanding of the behavior of replicating systems has important perspectives for both biology and chemistry.
- hydrogen bonds;
- molecular recognition;
- autocatalysis supramolecular chemistry;
- systems chemistry;
- template synthesis