Chapter 14. Chemical Reactions with RNA and DNA Enzymes

  1. Udo H. Brinker and
  2. Jean-Luc Mieusset
  1. Andres Jäschke

Published Online: 13 JUL 2010

DOI: 10.1002/9780470664872.ch14

Molecular Encapsulation: Organic Reactions in Constrained Systems

Molecular Encapsulation: Organic Reactions in Constrained Systems

How to Cite

Jäschke, A. (2010) Chemical Reactions with RNA and DNA Enzymes, in Molecular Encapsulation: Organic Reactions in Constrained Systems (eds U. H. Brinker and J.-L. Mieusset), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470664872.ch14

Editor Information

  1. Institut für Organische Chemie, Universität Wien, A–1090 Wien, Austria

Author Information

  1. Institut für Pharmazie und Molekulare Biotechnologie (IPMB), Universität Heidelberg, D-69120 Heidelberg, Germany

Publication History

  1. Published Online: 13 JUL 2010
  2. Published Print: 25 JUN 2010

ISBN Information

Print ISBN: 9780470998076

Online ISBN: 9780470664872

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Keywords:

  • RNA and DNA enzyme chemical reactions;
  • naturally occurring ribozyme catalysis;
  • artificial RNA and DNA catalyst generation;
  • basic (aptamer) SELEX protocol - and chemically synthesized DNA library;
  • tRNA role and ribosomal RNA in translation;
  • artificial ribozyme catalytic spectrum;
  • deoxyribozymes - DNA molecules with catalytic properties;
  • catalysis of C[BOND]C bond formation - by Diels-Alderase ribozymes;
  • ribozyme, its substrates and product interaction;
  • conformational dynamics and metal ion role

Summary

This chapter contains sections titled:

  • Introduction

  • Catalysis by Naturally Occurring Ribozymes

  • How to Generate Artificial RNA and DNA Catalysts

  • The Catalytic Spectrum of Artificial Ribozymes

  • Deoxyribozymes – DNA Molecules with Catalytic Properties

  • Catalysis of C[BOND]C Bond Formation by Diels–Alderase Ribozymes

  • Conclusion

  • References