Chapter 2. Cyclodextrins

  1. Udo H. Brinker and
  2. Jean-Luc Mieusset
  1. Ronald Breslow

Published Online: 13 JUL 2010

DOI: 10.1002/9780470664872.ch2

Molecular Encapsulation: Organic Reactions in Constrained Systems

Molecular Encapsulation: Organic Reactions in Constrained Systems

How to Cite

Breslow, R. (2010) Cyclodextrins, in Molecular Encapsulation: Organic Reactions in Constrained Systems (eds U. H. Brinker and J.-L. Mieusset), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470664872.ch2

Editor Information

  1. Institut für Organische Chemie, Universität Wien, A–1090 Wien, Austria

Author Information

  1. Department of Chemistry, Columbia University, New York, NY 10027, USA

Publication History

  1. Published Online: 13 JUL 2010
  2. Published Print: 25 JUN 2010

ISBN Information

Print ISBN: 9780470998076

Online ISBN: 9780470664872



  • cyclodextrins;
  • cyclodextrin acylation by bound substrates;
  • catalytic reactions in cyclodextrin cavities - aromatic substitution;
  • catalytic reactions, by cyclodextrins with covalently attached catalytic groups;
  • binding by cyclodextrins and their dimers and trimers - transaminase mimics;
  • mimics of enzymes - using thiamine pyrophosphate as co-enzymes;
  • aldol condensations, catalysed by cyclodextrin derivatives;
  • mimics of enzymes - using coenzyme B12 as cofactor;
  • mimics of cytochrome P-450


This chapter contains sections titled:

  • Introduction

  • Acylations of the Cyclodextrins by Bound Substrates

  • Catalytic Reactions in Cyclodextrin Cavities: Aromatic Substitution

  • Other Solvents than Water

  • Catalytic Reactions Produced by Cyclodextrins With Covalently Attached Catalytic Groups

  • Binding by Cyclodextrins and their Dimers and Trimers

  • Mimics of Enzymes that Use Thiamine Pyrophosphate as a Co-Enzyme

  • Aldol Condensations Catalysed by Cyclodextrin Derivatives

  • Mimics of Enzymes Using Coenzyme B12 as a Cofactor

  • Mimics of Cytochrome P-450

  • Acknowledgements

  • References