Chapter 13. Whole Cell MALDI Mass Spectrometry for the Rapid Characterisation of Bacteria; A Survey of Applications to Major Lineages in the Microbial Kingdom

  1. Haroun N. Shah and
  2. Saheer E. Gharbia
  1. Ben van Baar

Published Online: 15 JUN 2010

DOI: 10.1002/9780470665497.ch13

Mass Spectrometry for Microbial Proteomics

Mass Spectrometry for Microbial Proteomics

How to Cite

van Baar, B. (2010) Whole Cell MALDI Mass Spectrometry for the Rapid Characterisation of Bacteria; A Survey of Applications to Major Lineages in the Microbial Kingdom, in Mass Spectrometry for Microbial Proteomics (eds H. N. Shah and S. E. Gharbia), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470665497.ch13

Editor Information

  1. Department for Bioanalysis and Horizon Technologies, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK

Author Information

  1. TNO Defence, Security and Safety, PO Box 45, NL-2280 AA Rijswijk, The Netherlands

Publication History

  1. Published Online: 15 JUN 2010
  2. Published Print: 23 JUL 2010

ISBN Information

Print ISBN: 9780470681992

Online ISBN: 9780470665497

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Keywords:

  • targeted molecules and specific microorganism analysis;
  • whole cell MALDI mass spectrometry for rapid bacteria characterisation-major lineages in microbial kingdom;
  • Mass spectrometry (MS)-toolbox for investigation of systems and processes of life;
  • multi-locus sequence typing (MLST);
  • factors concerning MALDI MS process;
  • whole cell MALDI MS of particular bacteria genera and species;
  • Gram-negative food- and waterborne pathogen proteobacteria other than E. coli;
  • biomarker identification strategies-in whole cell MALDI MS spectra;
  • on-target treatment and analysis;
  • ‘Off-Target’ analysis and correlation with proteomics studies

Summary

This chapter contains sections titled:

  • Introduction

  • Scope

  • Reproducibility

  • Whole Cell MALDI MS of Particular Bacteria Genera and Species

  • Strategies for the Identification of Biomarkers in Whole Cell MALDI MS Spectra

  • Conclusions and Outlook

  • References