Chapter 3. Overview of Proteomic Tools and Their Links to Genomics

  1. Haroun N. Shah and
  2. Saheer E. Gharbia
  1. Raju Misra

Published Online: 15 JUN 2010

DOI: 10.1002/9780470665497.ch3

Mass Spectrometry for Microbial Proteomics

Mass Spectrometry for Microbial Proteomics

How to Cite

Misra, R. (2010) Overview of Proteomic Tools and Their Links to Genomics, in Mass Spectrometry for Microbial Proteomics (eds H. N. Shah and S. E. Gharbia), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470665497.ch3

Editor Information

  1. Department for Bioanalysis and Horizon Technologies, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK

Author Information

  1. Department for Bioanalysis and Horizon Technologies, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK

Publication History

  1. Published Online: 15 JUN 2010
  2. Published Print: 23 JUL 2010

ISBN Information

Print ISBN: 9780470681992

Online ISBN: 9780470665497

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Keywords:

  • proteomics tools and biomarker discovery;
  • proteomic tools and links to genomics;
  • protein identification, correct assignment of mass spectrometry spectrum to peptide and proteomic data processing;
  • protein identification – rapid, accurate identification of proteins/peptides from mass spectra-through bioinformatic analyses;
  • MS methods and instrument configurations-for microorganism analysis;
  • simplified peptide identification pathway-by peptide fragment fingerprint (PFF) database searching;
  • Peptide Fragment Fingerprint-alternatives to PMF method;
  • PMF and PFF based protein identifications-identifying protein/peptide sequence;
  • False Discovery Rate (FDR);
  • applications-and biomarker discovery

Summary

This chapter contains sections titled:

  • Introduction

  • Protein Identification

  • Applications

  • References