Chapter 2. Unraveling the Pathogenesis of the Depression–Diabetes Link

  1. Wayne Katon2,
  2. Mario Maj3 and
  3. Norman Sartorius4
  1. Khalida Ismail

Published Online: 3 AUG 2010

DOI: 10.1002/9780470667309.ch2

Depression and Diabetes

Depression and Diabetes

How to Cite

Ismail, K. (2010) Unraveling the Pathogenesis of the Depression–Diabetes Link, in Depression and Diabetes (eds W. Katon, M. Maj and N. Sartorius), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470667309.ch2

Editor Information

  1. 2

    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA

  2. 3

    Department of Psychiatry, University of Naples SUN, Naples, Italy

  3. 4

    Association for the Improvement of Mental Health Programmes, Geneva, Switzerland

Author Information

  1. Department of Psychological Medicine, Institute of Psychiatry, King's College London, London, UK

Publication History

  1. Published Online: 3 AUG 2010
  2. Published Print: 27 AUG 2010

ISBN Information

Print ISBN: 9780470688380

Online ISBN: 9780470667309

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Keywords:

  • Unraveling the Pathogenesis of the Depression–Diabetes Link;
  • limitations of the psychological model;
  • coronary artery disease (CAD);
  • depression and insulin resistance;
  • Depression and Activity of the Hypothalamic–Pituitary–Adrenal (HPA) Axis;
  • The Diabetes–Depression Link and the Autonomic Nervous System;
  • The Diabetes–Depression Link and the Innate Inflammatory Response;
  • Genetics of the Diabetes–Depression Link;
  • The Diabetes–Depression Link and Birth Weight;
  • The Diabetes–Depression Link and Early Childhood Adversity

Summary

This chapter contains sections titled:

  • Limitations of the Psychological Model

  • Depression and Insulin Resistance

  • Depression and Activity of the Hypothalamic–Pituitary–Adrenal (HPA) Axis

  • The Diabetes–Depression Link and the Autonomic Nervous System

  • The Diabetes–Depression Link and the Innate Inflammatory Response

  • Genetics of the Diabetes–Depression Link

  • The Diabetes–Depression Link and Birth Weight

  • The Diabetes–Depression Link and Early Childhood Adversity

  • The Role of Antidepressants

  • Conclusions

  • References