2. Biomarkers in Heart Failure

  1. Barry H. Greenberg2,
  2. Denise D. Barnard2,
  3. Sanjiv M. Narayan3 and
  4. John R. Teerlink4,5
  1. Leo Slavin MD2,
  2. Thomas K. Ro MD2 and
  3. Alan S. Maisel MD, FACC1

Published Online: 14 SEP 2010

DOI: 10.1002/9780470669402.ch2

Management of Heart Failure

Management of Heart Failure

How to Cite

Slavin, L., Ro, T. K. and Maisel, A. S. (2010) Biomarkers in Heart Failure, in Management of Heart Failure (eds B. H. Greenberg, D. D. Barnard, S. M. Narayan and J. R. Teerlink), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470669402.ch2

Editor Information

  1. 2

    Division of Cardiology, University of California, San Diego, California, USA

  2. 3

    University of California and Veterans Affairs Medical Center, San Diego, California, USA

  3. 4

    Section of Cardiology, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA

  4. 5

    School of Medicine, University of California, San Francisco, California, USA

Author Information

  1. 1

    Coronary Care Unit and Heart Failure Program, Veterans Affairs San Diego Healthcare System, and University of California, San Diego, California, USA

  2. 2

    Division of Cardiology, University of California, San Diego, California, USA

Publication History

  1. Published Online: 14 SEP 2010
  2. Published Print: 8 OCT 2010

ISBN Information

Print ISBN: 9780470753798

Online ISBN: 9780470669402

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Keywords:

  • biomarkers in heart failure;
  • heart failure (HF), serious public health matters in modern medicine;
  • Natriuretic peptides (NP), released by cardiac myocytes - in response to wall stress from intravascular volume expansion;
  • desired properties - of ideal biomarker;
  • natriuretic peptide subtypes and their actions;
  • synthesis and processing of B-type natriuretic peptide;
  • non-NP biomarkers of interest in heart failure;
  • MR-proADM, new biomarker - reflecting myocardial stretch, increasing in patients with HF;
  • neutrophil gelatinase-associated lipocalin (NGAL);
  • biomarker role, emerging as important tool - in basic and clinical heart failure

Summary

This chapter contains sections titled:

  • Introduction

  • Biomarkers

  • Natriuretic peptides

  • Non-natriuretic peptides of interest in heart failure

  • ST-2

  • Adrenomedullin

  • Troponin

  • C-reactive protein

  • Neutrophil gelatinase-associated lipocalin (NGAL)

  • The future

  • References