7. Emerging Therapies for Heart Failure

  1. Barry H. Greenberg2,
  2. Denise D. Barnard2,
  3. Sanjiv M. Narayan3 and
  4. John R. Teerlink4,5
  1. Barry H. Greenberg MD2 and
  2. John G. F. Cleland MD, FRCP, FESC, FACC1

Published Online: 14 SEP 2010

DOI: 10.1002/9780470669402.ch7

Management of Heart Failure

Management of Heart Failure

How to Cite

Greenberg, B. H. and Cleland, J. G. F. (2010) Emerging Therapies for Heart Failure, in Management of Heart Failure (eds B. H. Greenberg, D. D. Barnard, S. M. Narayan and J. R. Teerlink), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470669402.ch7

Editor Information

  1. 2

    Division of Cardiology, University of California, San Diego, California, USA

  2. 3

    University of California and Veterans Affairs Medical Center, San Diego, California, USA

  3. 4

    Section of Cardiology, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA

  4. 5

    School of Medicine, University of California, San Francisco, California, USA

Author Information

  1. 1

    Castle Hill Hospital, University of Hull, Kingston-upon-Hull, East Riding of Yorkshire, UK

  2. 2

    Division of Cardiology, University of California, San Diego, California, USA

Publication History

  1. Published Online: 14 SEP 2010
  2. Published Print: 8 OCT 2010

ISBN Information

Print ISBN: 9780470753798

Online ISBN: 9780470669402



  • emerging therapies for heart failure;
  • heart failure, major global public health problem - increasing in magnitude over the coming years;
  • estimated reduction in CHD/stroke of a Polypill - in those with average risk factor levels;
  • coronary artery disease, and MI - recognized as extremely important cause of heart failure;
  • public health issue of growing importance - around the world, striking increase in prevalence of obesity;
  • conventional inotropic agents - increasing velocity and force of myocardial contraction;
  • major calcium handling abnormalities - in failing heart;
  • carnitine palmitoyl transferase inhibitors;
  • mechanism of arterial dilation with relaxin;
  • cell transplantation therapy


This chapter contains sections titled:

  • Introduction

  • Can heart failure be prevented?

  • New drugs

  • Gene transfer

  • Cell transplantation therapy

  • References