Chapter 3. Solid Phase Extraction

  1. John R. Dean B.Sc., M.Sc., Ph.D., D.I.C., D.Sc., FRSC, C.Chem., C.Sci., Cert. Ed., Registered Analytical Chemist postdoctoral research fellow Senior Lecturer Reader Principal Lecturer Associate Dean personal chair Director Professor recipient active member Past Chairman former Vice-President

Published Online: 29 DEC 2009

DOI: 10.1002/9780470682494.ch3

Extraction Techniques in Analytical Sciences

Extraction Techniques in Analytical Sciences

How to Cite

Dean, J. R. (2009) Solid Phase Extraction, in Extraction Techniques in Analytical Sciences, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470682494.ch3

Author Information

  1. The Graduate School and School of Applied Sciences, Northumbria University, Newcastle, UK

Publication History

  1. Published Online: 29 DEC 2009
  2. Published Print: 7 NOV 2009

Book Series:

  1. Analytical Techniques in the Sciences

Book Series Editors:

  1. David J. Ando

Series Editor Information

  1. Dartford, Kent, UK

ISBN Information

Print ISBN: 9780470772850

Online ISBN: 9780470682494



  • solid phase extraction (SPE) - isolation, enrichment of components of interest from aqueous samples;
  • choice of sorbent and solvent system for effective pre-concentration;
  • SPE media (sorbent) types;
  • molecularly imprinted polymers (MIPs) - as sorbents in SPE;
  • SPE formats and apparatus;
  • SPE operation method;
  • GC analysis using thermionic specific detection (TSD) and electron capture detection (ECD);
  • ‘SupelMIP’ SPE chloramphenicol cartridges;
  • automation and on-line SPE;
  • ‘Oasis’ hydrophilic–lipophilic balance (HLB) extraction cartridge


This chapter contains sections titled:

  • Introduction

  • Types of SPE Media (Sorbent)

  • SPE Formats and Apparatus

  • Method of SPE Operation

  • Solvent Selection

  • Factors Affecting SPE

  • Selected Methods of Analysis for SPE

  • Automation and On-Line SPE

  • References