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Directed Metallation of Aromatic Compounds

Organolithium Compounds (2004)

  1. Jonathan Clayden

Published Online: 15 DEC 2009

DOI: 10.1002/9780470682531.pat0306

Patai's Chemistry of Functional Groups

Patai's Chemistry of Functional Groups

How to Cite

Clayden, J. 2009. Directed Metallation of Aromatic Compounds. Patai's Chemistry of Functional Groups. .

Author Information

  1. University of Manchester, Department of Chemistry, Manchester, UK

Publication History

  1. Published Online: 15 DEC 2009

Abstract

  • 1
    Ortholithiation of Carbocyclic Aromatic Compounds
  • 2
    Ortholithiation of Aromatic Heterocycles
  • 3
    Lithiation of Metal–Arene Complexes
  • 4
    Lateral Lithiation
  • 5
    Remote Lithiation, and β-Lithiation of Non-Aromatic Compounds
  • 6
    Superbases477
  • 7
    Cooperation, Competition and Regioselectivity

Keywords:

  • aromatic compound directed metallation;
  • carbocyclic aromatic compound ortholithiation;
  • classes of directing group;
  • aminomethyl groups;
  • O class - ethers and alkoxides;
  • stereoselective ortholithiation;
  • aromatic heterocycle ortholithiation;
  • electron-deficient heterocycles and electron-rich heterocycles