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Theory of Organocopper-Mediated Reactions

Organocopper Compounds (2009)

  1. Eiichi Nakamura,
  2. Naohiko Yoshikai

Published Online: 17 JAN 2011

DOI: 10.1002/9780470682531.pat0434

Patai's Chemistry of Functional Groups

Patai's Chemistry of Functional Groups

How to Cite

Nakamura, E. and Yoshikai, N. 2011. Theory of Organocopper-Mediated Reactions. Patai's Chemistry of Functional Groups. .

Author Information

  1. The University of Tokyo, Department of Chemistry, Hongo, Bunkyo-ku, Tokyo, Japan

Publication History

  1. Published Online: 17 JAN 2011

Abstract

  • 1
    Introduction
  • 2
    Structure and Reactivity of Organocopper Compounds
  • 3
    Conjugate Addition versus SN2 Alkylation Reactions
  • 4
    Allylation, Alkenylation and Acylation Reactions
  • 5
    Effect of Lewis Acid and Lewis Base
  • 6
    Concluding Remarks

Keywords:

  • theory of organocopper-mediated reactions;
  • organocopper compounds in organic chemistry - in the form of nucleophilic organocopper(I) reagents;
  • history of nucleophilic organocopper chemistry;
  • dominant part of synthetic organocopper chemistry - and synthesis of biologically active compounds;
  • structure and reactivity of organocopper compounds;
  • conjugate addition to α,β-unsaturated carbonyl compound;
  • carbocupration of acetylene providing - reliable stereoselective route to cis-alkenylcopper (I) species;
  • allylation, alkenylation and acylation reactions