Organic Transformations Promoted by Lewis Acid Iron Catalysts
Organoiron Compounds (2013)
Published Online: 17 JUN 2013
Copyright © 2009 John Wiley & Sons, Ltd. All rights reserved.
Patai's Chemistry of Functional Groups
How to Cite
Vrancken, E. and Campagne, J.-M. 2013. Organic Transformations Promoted by Lewis Acid Iron Catalysts. Patai's Chemistry of Functional Groups.
- Published Online: 17 JUN 2013
Iron salts of high oxidation states, Fe(II) and Fe(III), possess strong Lewis acid properties and are able to activate a wide range of functionalities. These properties, associated with low toxicity, abundance, low price together with more practical aspects, are witnessed by the blossoming of this field in the last few years. Beyond traditional activation of CX and CX bonds, more recent applications involving the generation of iron enolates and oxocarbeniums species, and the activation of CC and CC bonds are surveyed. A special emphasis is given to successive electrophilic and/or nucleophilic activations of different functionalities, which allow domino and one-pot processes.
- Lewis acid;
- direct substitution;
- polar reactions;