Chapter 17. Prevention and Treatment of Diabetic Nephropathy: The Role of Blood Pressure Lowering

  1. William H. Herman2,
  2. Ann Louise Kinmonth3,
  3. Nicholas J. Wareham4 and
  4. Rhys Williams5
  1. Carl Erik Mogensen

Published Online: 12 JAN 2010

DOI: 10.1002/9780470682807.ch17

The Evidence Base for Diabetes Care, Second Edition

The Evidence Base for Diabetes Care, Second Edition

How to Cite

Mogensen, C. E. (2010) Prevention and Treatment of Diabetic Nephropathy: The Role of Blood Pressure Lowering, in The Evidence Base for Diabetes Care, Second Edition (eds W. H. Herman, A. L. Kinmonth, N. J. Wareham and R. Williams), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470682807.ch17

Editor Information

  1. 2

    Department of Internal Medicine and Epidemiology, University of Michigan, Ann Arbor, MI, USA

  2. 3

    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

  3. 4

    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK

  4. 5

    School of Medicine, Swansea University, Swansea, UK

Author Information

  1. Department of Internal Medicine M (Diabetes and Endocrinology), Aarhus University Hospital, Aarhus, Denmark

Publication History

  1. Published Online: 12 JAN 2010
  2. Published Print: 19 FEB 2010

ISBN Information

Print ISBN: 9780470032749

Online ISBN: 9780470682807

SEARCH

Keywords:

  • diabetic nephropathy prevention and treatment - blood pressure lowering role;
  • diabetic nephropathy patients - dying from cardiovascular disease before progression to end-stage renal disease (ESRD);
  • role of local blood pressure (BP) level in structural damage, not seen in post-stenotic kidney;
  • new meta-analysis of BP lowering;
  • increased BP, major risk factor for diabetic renal disease progression;
  • Diabetics Exposed to Telmisartan And enalaprIL (DETAIL) trial;
  • effect of ACE-i and ARBs on renal outcomes and mortality;
  • Bergamo Nephrologic Diabetes Complications Trial (BENEDICT);
  • microalbuminuria prevention - steps in diabetic kidney disease prevention;
  • regression or remission of albuminuria - a new paradigm shift

Summary

This chapter contains sections titled:

  • Introduction

  • New meta-analysis of BP lowering

  • Meta-analysis and the effect of ACE-i and ARBs on renal outcomes and mortality

  • Preventing microalbuminuria in diabetes

  • Regression of albuminuria: a new paradigm shift

  • References