Chapter 7. The Effectiveness of Interventions Aimed at Weight Loss and other Effects of Diet and Physical Activity in Achieving Control of Diabetes and Preventing its Complications

  1. William H. Herman2,
  2. Ann Louise Kinmonth3,
  3. Nicholas J. Wareham4 and
  4. Rhys Williams5
  1. Nita Gandhi Forouhi1 and
  2. Nicholas J. Wareham4

Published Online: 12 JAN 2010

DOI: 10.1002/9780470682807.ch7

The Evidence Base for Diabetes Care, Second Edition

The Evidence Base for Diabetes Care, Second Edition

How to Cite

Gandhi Forouhi, N. and Wareham, N. J. (2010) The Effectiveness of Interventions Aimed at Weight Loss and other Effects of Diet and Physical Activity in Achieving Control of Diabetes and Preventing its Complications, in The Evidence Base for Diabetes Care, Second Edition (eds W. H. Herman, A. L. Kinmonth, N. J. Wareham and R. Williams), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470682807.ch7

Editor Information

  1. 2

    Department of Internal Medicine and Epidemiology, University of Michigan, Ann Arbor, MI, USA

  2. 3

    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

  3. 4

    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK

  4. 5

    School of Medicine, Swansea University, Swansea, UK

Author Information

  1. 1

    Elsie Widdowson Laboratory, MRC Epidemiology Unit, Cambridge, UK

  2. 4

    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK

Publication History

  1. Published Online: 12 JAN 2010
  2. Published Print: 19 FEB 2010

ISBN Information

Print ISBN: 9780470032749

Online ISBN: 9780470682807

SEARCH

Keywords:

  • effectiveness;
  • interventions;
  • weight loss;
  • diet;
  • physical activity;
  • diabetes mellitus;
  • prevention;
  • complications

Summary

Weight loss is widely promoted as a key element of the management of type 2 diabetes. This chapter reviews evidence for the effectiveness of a range of different interventions on weight loss and diabetes control. These interventions predominantly focus on lifestyle change and the review considers the nature of diet and physical activity interventions that are likely to be most beneficial for weight loss, but also the potential impact of changes in these behaviours on metabolic control independent of weight loss. The effect of surgical and pharmacological interventions on weight loss and diabetes control is also reviewed. Finally, the review considers prospects for long-term trials of behavioural interventions that examine the complications of diabetes as endpoints rather than intermediate proxy outcomes