Chapter 1. Introduction

  1. John Kelly

Published Online: 13 NOV 2009

DOI: 10.1002/9780470682920.ch1

Principles of CNS Drug Development: From Test Tube to Patient

Principles of CNS Drug Development: From Test Tube to Patient

How to Cite

Kelly, J. (2010) Introduction, in Principles of CNS Drug Development: From Test Tube to Patient, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470682920.ch1

Author Information

  1. Department of Pharmacology and Therapeutics, National University of Ireland, Galway, Ireland

Publication History

  1. Published Online: 13 NOV 2009
  2. Published Print: 8 JAN 2010

ISBN Information

Print ISBN: 9780470519790

Online ISBN: 9780470682920

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Keywords:

  • central nervous system (CNS) diseases - early stage of life to later-age onset;
  • pharmacological treatment of brain disorders - having greater complexity;
  • global burden of CNS disease;
  • CNS disorders - bipolar disorder, epilepsy and schizophrenia;
  • World Health Organization (WHO) and its first Global Burden of Disease (GBD);
  • global death estimates and CNS disorders;
  • disability classes for certain CNS disorders;
  • CNS disorders and disability;
  • CNS disorders - leading causes of YLD (years lost to disability);
  • Global DALYs estimate for neuropsychiatric disorders

Summary

This chapter contains sections titled:

  • The global burden of CNS disease

  • Assessment of the global burden of disease

  • The prevalence of CNS disorders

  • Disability due to CNS disorders

  • Economic Costs

  • Concluding comments

  • References