Chapter 9. Repeatability, Reproducibility and Coefficient of Variation

  1. Bendix Carstensen1,2

Published Online: 24 JUN 2010

DOI: 10.1002/9780470683019.ch9

Comparing Clinical Measurement Methods: A Practical Guide

Comparing Clinical Measurement Methods: A Practical Guide

How to Cite

Carstensen, B. (2010) Repeatability, Reproducibility and Coefficient of Variation, in Comparing Clinical Measurement Methods: A Practical Guide, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470683019.ch9

Author Information

  1. 1

    Steno Diabetes Center, Gentofte, Denmark

  2. 2

    Department of Biostatistics, University of Copenhagen, Denmark

Publication History

  1. Published Online: 24 JUN 2010
  2. Published Print: 13 AUG 2010

ISBN Information

Print ISBN: 9780470694237

Online ISBN: 9780470683019

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Keywords:

  • repeatability, reproducibility and coefficient of variation;
  • assessment of method-specific repeatability and reproducibility - interest in its own right;
  • repeatability and reproducibility - assessed when replicate measurements by each method are available;
  • repeatability coefficient - as upper limit of a prediction interval;
  • reproducibility coefficient of method - as upper limits of prediction interval;
  • measurement method precision - given as coefficient of variation (CV);
  • measurement error assumed proportional to the mean - multiplicative structure for errors;
  • log-transformed data estimating CV - data transformation prior to data analysis;
  • Box–Cox family

Summary

This chapter contains sections titled:

  • Repeatability

  • Reproducibility

  • Coefficient of variation