Chapter 1. Biomarkers and Bioinformatics

  1. Dr Francisco Azuaje Senior Member Associate Editor

Published Online: 14 JAN 2010

DOI: 10.1002/9780470686423.ch1

Bioinformatics and Biomarker Discovery: “Omic” Data Analysis for Personalized Medicine

Bioinformatics and Biomarker Discovery: “Omic” Data Analysis for Personalized Medicine

How to Cite

Azuaje, F. (2010) Biomarkers and Bioinformatics, in Bioinformatics and Biomarker Discovery: “Omic” Data Analysis for Personalized Medicine, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470686423.ch1

Author Information

  1. Public Research Centre for Health (CRP-Santé), Luxembourg

Publication History

  1. Published Online: 14 JAN 2010
  2. Published Print: 19 FEB 2010

ISBN Information

Print ISBN: 9780470744604

Online ISBN: 9780470686423

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Keywords:

  • translational bioinformatics;
  • biomarkers;
  • personalized medicine;
  • biomedical informatics;
  • diagnosis;
  • prognosis

Summary

This chapter presents an introduction to bioinformatics in the context of translational biomedical research. Different roles of bioinformatics in supporting the development of personalized medicine are explained. Biomarkers and types of biomarkers are defined. This chapter introduces the application of clinical and molecular information in biomarker discovery research. Fundamental computational approaches to biomarker discovery are described, together with a discussion on key applications and challenges. Examples of biomarkers, prediction models and applications in different medical areas are offered. The chapter concludes with an overview of the book contents