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Brucella

Bacteriology

Organisms and Their Biology

  1. Patrick R. Murray PhD Chief1,
  2. Michael J. Corbel PHD DSC(Med) FIBiol FRCPATH Head2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0066

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Murray, P. R. and Corbel, M. J. 2010. Brucella. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    National Institutes of Health Clinical Center, Microbiology Service, Department of Laboratory Medicine, Bethesda, MD, USA

  2. 2

    National Institute of Biological Standards and Control, Division of Bacteriology, Potters Bar, Hertfordshire, UK

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction and History
  • 2
    Definition
  • 3
    Habitat
  • 4
    Morphology
  • 5
    Cellular Composition
  • 6
    Antigenic Structure
  • 7
    Genetics
  • 8
    Metabolism and Biochemical Properties
  • 9
    Susceptibility to Physical and Chemical Agents
  • 10
    Cultural Aspects
  • 11
    Virulence and Pathogenicity
  • 12
    Summarized Descriptions of Species
  • 13
    Acknowledgments

Keywords:

  • Brucella - type of fever, fairly regular remissions or intermissions;
  • B. melitensis, and B. suis - virulence associated with smooth colonial form;
  • Brucellae - small nonmotile, nonsporing, gram-negative coccobacilli, or short rods;
  • antigenic composition of Brucella cell surface varying with colonial phase of organism;
  • polysaccharides structurally related to Brucella LPS O chain;
  • average genome complexity for Brucella and closely related Ochrobactrum and Phyllobacterium genera;
  • biohazard aspects - Brucella strains, implicated in laboratory-acquired infections;
  • Brucella sp. isolation - in reaching a diagnosis