Standard Article

Coxiella burnetii

Bacteriology

Organisms and Their Biology

  1. Nigel F. Lightfoot MBBS MRCPath MSc Director of Emergency Response1,
  2. Graham Lloyd PhD MS BS FBMS2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0081

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Lightfoot, N. F. and Lloyd, G. 2010. Coxiella burnetii. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Health Protection Agency, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, UK

  2. 2

    Health Protection Agency, Head of Special Pathogens Reference Unit, Novel and Dangerous Pathogens, Centre for Emergency Preparedness and Response, Porton Down, Salisbury, UK

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Classification
  • 3
    Habitat
  • 4
    Microenvironment and Morphology
  • 5
    Laboratory Isolation, Cultural Characteristics, and Growth Requirements
  • 6
    Morphology – Genome and Plasmids
  • 7
    Structure–Cell Wall Composition and Antigenic Properties
  • 8
    Transmission, Pathogenesis, and Clinical Symptoms
  • 9
    Laboratory Diagnosis
  • 10
    Treatment – Sensitivity to Antibiotics
  • 11
    Epidemiology and Control

Keywords:

  • Coxiella burnetii, intracellular, gram-negative acidophile bacterium;
  • Coxiella burnetii-category B bioterrorism agent;
  • Coxiella burnetii, category B bioterrorism agent-highly infective in humans and livestock;
  • shell vial culture technique and Eagle's minimal essential medium (MEM);
  • Coxiella isolation by plaque formation and minced in Earle's balanced salt solution (EBSS);
  • restriction fragment length polymorphism (RLPF) patterns of genomic DNA by PFGE;
  • transmission, pathogenesis and clinical symptoms;
  • Q fever-natural infection mechanism, in man by inhalation route and human to human transmission