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Pattern Recognition

Immunology

Innate Immunity and Infection

  1. Nicolas W.J. Schröder MD1,
  2. Ralf R. Schumann MD PhD Professor of Medicine and Microbiolobgy2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0088

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Schröder, N. W. and Schumann, R. R. 2010. Pattern Recognition. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Medical Faculty of The Humboldt-University, Institute for Microbiology and Hygiene, ‘Charité’ University Medical Center, Berlin, Germany

  2. 2

    Medical Faculty of The Humboldt-University, Institute for Microbiology and Hygiene, ‘Charité’ University Medical Center, Berlin, Germany

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Brief Historic Introduction
  • 2
    Microbial Toxins
  • 3
    Molecular Patterns of Pathogens
  • 4
    Innate Immunity
  • 5
    Cells of the Innate Immune System
  • 6
    Pattern Recognition Receptors
  • 7
    The Family of Toll-Like Receptors
  • 8
    Signal Transduction Cascade Induced by TLR–Ligand Interaction
  • 9
    Links to Adaptive Immunity
  • 10
    A Two-Step Model of Pattern Recognition
  • 11
    Clinical Implications and Conclusions
  • 12
    Conclusion

Keywords:

  • pattern recognition;
  • microbial toxins;
  • ‘Putrid poison’, ‘sepsin’ and birth of microbiology;
  • host–pathogen interaction-causes of diseases of importance;
  • microorganisms and their hosts-‘battle of the genomes’;
  • cells of innate immune system;
  • pattern recognition receptors;
  • signal transduction cascade induced by TLR–ligand interaction