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Apoptosis

Immunology

Innate Immunity and Infection

  1. Antoine Galmiche MD PhD1,
  2. Arturo Zychlinsky2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0089

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Galmiche, A. and Zychlinsky, A. 2010. Apoptosis. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Department of Cellular Microbiology, Max Planck Institute fur Ifektions Biologie, Berlin, Germany

  2. 2

    Max Planck Institut fur Infektions Biologie, Department of Cellular Microbiology, Berlin, Germany

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    The Induction of Apoptosis: Extrinsic Versus Intrinsic Pathways
  • 3
    Mitochondria
  • 4
    Caspases
  • 5
    Basic Cellular Mechanisms and Regulation
  • 6
    What Happens After Death?
  • 7
    Bacterial-Induced Apoptosis
  • 8
    Conclusion
  • 9
    Acknowledgments

Keywords:

  • induction of apoptosis-extrinsic versus intrinsic pathways;
  • multicellular organisms-cells often dying by apoptosis;
  • pro-survival members of Bcl-2 family;
  • mitochondrial outer membrane (MOM)-permeable to solutes of small size;
  • pro-apoptotic members of Bcl-2 family;
  • proteolytic cleavage between constitutive domains;
  • basic cellular mechanisms and regulation;
  • bacterial pathogens-inducing apoptosis by variety of mechanisms