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The Acute Phase Response

Immunology

Innate Immunity and Infection

  1. John G. Raynes BSc PhD Senior Lecturer

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0093

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Raynes, J. G. 2010. The Acute Phase Response. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. London School of Hygiene and Tropical Medicine, London, UK

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Induction of the Acute Phase Response
  • 3
    Acute Phase Proteins
  • 4
    Hemopoietic Responses
  • 5
    Metabolic Changes
  • 6
    Hormonal Changes
  • 7
    Fever and Other Behavioral Changes
  • 8
    Control of Systemic Inflammation
  • 9
    Disorders of the Acute Phase Response

Keywords:

  • acute phase response (APR), conserved response;
  • ‘systemic inflammatory response syndrome (SIRS)’;
  • liver protective responses;
  • acute phase response induction;
  • proinflammatory cytokines and acute phase proteins;
  • acute phase proteins;
  • C-reactive protein and other pentraxins;
  • lipopolysaccharide-binding protein (LBP)