Standard Article

MHC Class I Antigen Processing System

Immunology

Acquired Immunity

  1. Jonathan W. Yewdell

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0102

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Yewdell, J. W. 2010. MHC Class I Antigen Processing System. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. National Institute of Allergy and Infectious Diseases, Laboratory of Viral Diseases, Bethesda, MD, USA

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Evolutionary Context: Overview of the Adaptive Cellular Immune System
  • 2
    Antigen Processing: Step by Step

Keywords:

  • MHC class I antigen processing system;
  • adaptive cellular immune system;
  • DCs, role in generating CD8+ T-cell responses;
  • antigen processing-step by step;
  • class I peptide ligands and binding rules;
  • exogenous peptide presentation and practical issues;
  • class I assembly and surface expression;
  • nonproteasomal cytosolic proteases in antigen processing