Standard Article

Viral Interference with the Host Immune Response

Immunology

Infection and Immunity

  1. Antonio Alcami PHFD Senior Research Assistant1,2,
  2. Ann B. Hill MB BS FRACP PhD Associate Professor3,
  3. Ulrich H. Koszinowski4

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0112

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Alcami, A., Hill, A. B. and Koszinowski, U. H. 2010. Viral Interference with the Host Immune Response. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    University of Cambridge, Department of Medicine, Addenbrooke's Hospital, Cambridge, UK

  2. 2

    Centro Nacional de Biotecnologia (CSIC), Campus Universidad Autonoma, Madrid, Spain

  3. 3

    Oregon Health and Science University, Department of Molecular Microbiology and Immunology, Portland, OR, USA

  4. 4

    Max von Pettenkofer-Institut, Chair of Virology, München, Germany

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Effects on Molecules that Signal Between Cells
  • 3
    Apoptosis
  • 4
    Cellular Effector Cells of Innate Immunity
  • 5
    Effects on the Adaptive Immune Response
  • 6
    Conclusions
  • 7
    Acknowledgments

Keywords:

  • iral interference with host immune response;
  • clearance of viruses from infected tissues and coordinated scenario of multiple effector functions;
  • immune response natural killer (NK) cells forming second line of defense;
  • adaptive immune response effects;
  • viral modulation of IFN effector functions;
  • secreted viral cytokine receptors;
  • mitochondrial apoptosis regulation;
  • viral interference significance with CD8 function in vivo