Standard Article

Shock/Sepsis

Immunology

Immunopathology and Immunodeficiency

  1. Daniela N. Männel

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0115

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Männel, D. N. 2010. Shock/Sepsis. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. University of Regensburg, Department of Immunology, Germany

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Introduction
  • 2
    Definitions
  • 3
    Mediators of Immune Reactions
  • 4
    Activation of the Cellular System
  • 5
    Activation of Humoral Systems
  • 6
    Circulatory Failure and Direct Cytotoxic Effects
  • 7
    Implications for Therapies
  • 8
    Acknowledgments

Keywords:

  • shock/sepsis;
  • systemic inflammatory response syndrome (SIRS);
  • multiple organ failure (MOF);
  • immune reaction mediators-pathogen-specific molecular pattern sensing;
  • tumor necrosis factor (TNF) and interleukin 1 (IL-1);
  • cellular system activation;
  • circulatory failure and direct cytotoxic effects;
  • counterregulation of inflammation