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Autoimmunity

Immunology

Immunopathology and Immunodeficiency

  1. Helena Crowley1,
  2. Brigitte T. Huber PhD2

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0118

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Crowley, H. and Huber, B. T. 2010. Autoimmunity. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Tufts University School of Medicine, Department of Pathology, Boston, MA, USA

  2. 2

    Tufts University School of Medicine, Department of Pathology, Boston, MA, USA

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Defining Autoimmunity and Autoimmune Disease
  • 2
    The Discovery and Rediscovery of Autoimmunity
  • 3
    Mechanisms of Tolerance
  • 4
    Genetics as a Factor in Autoimmune Disease Susceptibility
  • 5
    Environmental Factors and Autoimmune Disease
  • 6
    The Effects of Immune Disregulation on Autoimmune Disease Development
  • 7
    Mechanisms of Tissue Destruction and Organ Damage in Autoimmune Diseases
  • 8
    Experimental Animal Models of Autoimmunity
  • 9
    Autoimmunity through Immunization
  • 10
    Treatment Strategies for Autoimmune Disease
  • 11
    Conclusion

Keywords:

  • autoimmunity;
  • defining autoimmunity and autoimmune disease;
  • autoimmunity-discovery and rediscovery;
  • genetics, factor in autoimmune disease susceptibility;
  • immune disregulation effects on autoimmune disease development;
  • mechanisms of tissue destruction and organ damage in autoimmune diseases;
  • autoimmunity through immunization;
  • demyelination and axonal loss in MS (multiple sclerosis)