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Live Vaccine Carriers

Immunology

Vaccines

  1. Gordon Dougan Professor and Director1,
  2. Richard J. Aspinall BSc MBChB PhD MRCP2,
  3. Frances Bowe3,
  4. Liljana Petrovska DVM MSc PhD4

Published Online: 15 MAR 2010

DOI: 10.1002/9780470688618.taw0124

Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

How to Cite

Dougan, G., Aspinall, R. J., Bowe, F. and Petrovska, L. 2010. Live Vaccine Carriers. Topley and Wilson's Microbiology and Microbial Infections. .

Author Information

  1. 1

    Imperial College London, Centre for Molecular Microbiology and Infection, Department of Biological Sciences, London, UK

  2. 2

    Imperial College London, Centre for Molecular Microbiology and Infection, Department of Biological Sciences, London, UK

  3. 3

    Imperial College London, Centre for Molecular Microbiology and Infection, Department of Biological Sciences, London, UK

  4. 4

    Imperial College London, Centre for Molecular Microbiology and Infection, Department of Biological Sciences, London, UK

Publication History

  1. Published Online: 15 MAR 2010

Abstract

  • 1
    Live Vaccines are Inherently Immunogenic
  • 2
    Examples of Viral and Bacterial Vectors
  • 3
    Enhanced Targeting of the Immune System with Live Vectors
  • 4
    Influence of Route of Delivery
  • 5
    Conclusions
  • 6
    Acknowledgments

Keywords:

  • live vaccine carriers;
  • live vaccines, being inherently immunogenic;
  • live vaccines and enhanced immunogenicity;
  • combination of PAMPs associated with live vectors enhancing immunogenicity;
  • viral and bacterial vectors and attenuated viral vectors;
  • enhanced targeting of immune system with live vectors;
  • attenuated poxvirus vectors (NYVAC);
  • influence of route of delivery